QuickView for type I DNA topoisomerase;jsessionid=3884DBE72E648BCB5CD160CA4DE8151C;jsessionid=DD3E6F3902C272CA9A2C9523AE56A651 (gene)
- Gene Symbol:
- Top1
Mus musculus - Full name:
- topoisomerase (DNA) I
- Synonyms:
- AI467334, D130064I21Rik, Top-1, DNA topoisomerase 1, DNA topoisomerase I
- Genomic Location:
- Chr 2: 160471633-160548500
- Orthologs:
- Homo sapiens , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan): -
Predicted Gene Targets for miR-101 , Predicted Gene Targets for miR-139 , Predicted Gene Targets for miR-144 , Predicted Gene Targets for miR-141 , Predicted Gene Targets for miR-208 , Predicted Gene Targets for miR-23 , Predicted Gene Targets for miR-24 , Predicted Gene Targets for miR-25 , Predicted Gene Targets for miR-26 , Predicted Gene Targets for miR-27
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | proximal promoter sequence-specific DNA binding | isomerase activity | nucleic acid binding | protein-containing complex binding | ribonucleotide binding | nucleotide binding | supercoiled DNA binding | single-stranded DNA binding | carbohydrate derivative binding | protein serine/threonine kinase activity | catalytic activity | chromatin binding | protein domain specific binding | ATP binding | anion binding | adenyl nucleotide binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | purine nucleotide binding | ion binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | purine ribonucleoside triphosphate binding | protein binding | DNA topoisomerase type I activity | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | chromatin DNA binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | RNA polymerase II regulatory region sequence-specific DNA binding | protein kinase activity | transferase activity | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | kinase activity | heterocyclic compound binding | DNA topoisomerase activity | small molecule binding
GO Biological Process
RNA metabolic process | peptidyl-amino acid modification | cellular process | circadian regulation of gene expression | chromatin organization | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | chromosome segregation | cellular nitrogen compound biosynthetic process | circadian rhythm | protein serine/threonine kinase activity | rhythmic process | cellular nitrogen compound metabolic process | protein modification process | cellular biosynthetic process | embryo development | macromolecule modification | nitrogen compound metabolic process | multicellular organism development | phosphorus metabolic process | ncRNA transcription | regulation of gene expression | rRNA transcription | biosynthetic process | cell division | aromatic compound biosynthetic process | phosphorylation | rRNA metabolic process | protein phosphorylation | phosphate-containing compound metabolic process | DNA topological change | chromatin remodeling | protein metabolic process | DNA metabolic process | anatomical structure development | metabolic process | nucleobase-containing compound metabolic process | protein kinase activity | organic substance metabolic process | gene expression | transcription, DNA-templated | embryonic cleavage | cellular protein metabolic process | cellular macromolecule biosynthetic process | kinase activity | developmental process | organelle organization | peptidyl-serine phosphorylation | cellular protein modification process | ncRNA metabolic process | DNA conformation change | heterocycle metabolic process | chromosome organization | cellular metabolic process | DNA replication | macromolecule metabolic process | multicellular organismal process
GO Cellular Component
chromosome | intracellular membrane-bounded organelle | nuclear replication fork | somatodendritic compartment | fibrillar center | cell body | DNA topoisomerase complex (ATP-hydrolyzing) | cell | replication fork protection complex | nuclear lumen | neuronal cell body | ribonucleoprotein granule | replication fork | nucleolus | cytoplasm | intracellular organelle | P-body | dense fibrillar component | protein-containing complex | protein-DNA complex | nucleoplasm | perikaryon | nuclear chromosome | ribonucleoprotein complex | membrane-bounded organelle | nucleus | organelle | cytoplasmic ribonucleoprotein granule | membrane-enclosed lumen | intracellular
